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2015), the production of ROS and RNS also exerts a significant influence on impaired sleep homeostasis

The three-carbon sugar generated is glyceraldehyde-3-phosphate which can be shunted to glycolysis and oxidized to pyruvate

An imbalance between the supply and demand of oxygen [141,142,143] in the arterial wall leads to a hypoxic plaque microenvironment, mainly arising from the combination of increased cellular metabolic demand and reduced oxygen diffusion caused by thickening of the arterial wall during the development of atherosclerotic lesions [144]

Oxidative metabolites of curcumin inhibit IKK

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