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In addition to chemotherapy-induced POF, hUC-MSCs have shown therapeutic effects in autoimmune-induced POF rat or mouse models [119]

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These findings suggest that NNMT inhibition may influence tumor cell line phenotypes in vitro through both metabolic and epigenetic mechanisms, making 5-amino-1MQ a valuable tool for investigating the metabolic characteristics of different tumor cell lines

MD simulation Desmond was used for the MD simulation, with default protocols [15]
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