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The researchers also found that PPAR was up-regulated and FAO was enhanced in BRAF-mutated melanoma cells after MAPK inhibition therapy, leading to cancer cell resistance [131]

Curcumin therefore, protects chromatin substance against lead-mediated genotoxicity by stabilizing the activity of antioxidant defense structure [89]

Dec 2019;47:102201

This article was submitted to Plant Physiology, a section of the journal Frontiers in Plant Science Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Mechanisms include direct DNA binding, affecting transcription factor activity, and epigenetic modifications