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Description
R-spondin1 is essential in sex determination, skin differentiation and malignancy
This can stimulate angiogenesis at sites of tissue disruption in animal models ERK1/2 activation: Studies in preclinical settings have observed activation of extracellular signal-regulated kinases
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Diabetologia 65 , 13151327 (2022)
It has completed Phase 3 clinical trials (the REDEFINE program) with positive results, and Novo Nordisk is expected to seek FDA approval
