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Another study using NR supplementation showed that doses up to 1000 mg per day for 10 weeks were well tolerated in patients affected by mild cognitive impairments (MCI) 246

Therefore, the upregulation of catabolic pathways and the expression of cyst(e)ine transporters is often observed in cancer together with the upregulation of cysteine synthesis

Therefore, understanding the role of Gln metabolism in tumor progression is crucial

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Palmieri et al., 2006)