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While p53 modulators, including FOXO4-DRI, MDM2 inhibitors, and USP7 inhibitors have shown senolytic effects by selectively eliminating senescent cells or promoting their apoptosis in the laboratory, translating these findings to the clinic have so far been unsuccessful

Subsequently, the isolated DNA-protein complexes are dissolved again by heat treatment (Fig

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Metabolic Support: L-Carnitine plays a crucial role in transporting fatty acids into cells to be used for energy, thus supporting an efficient metabolism
