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The role of rs713041 glutathione peroxidase 4 (GPX4) single nucleotide polymorphism on disease susceptibility in humans: a systematic review and meta-analysis

This uncertainty creates a precautionary gap- both regulators and manufacturers may be cautious, delaying product approvals until more safety data are available

Zapata-Muoz J, Villarejo-Zori B, Largo-Barrientos P, Boya P

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The first publications reported enzyme activity involving displacement of a halide ion from an aromatic compound, resulting in an S-substituted glutathione conjugate (Mannervik et al., 2005)