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Thus, thermosensory neuronal signaling induces organismal HSR in response to acute heat stress, but suppresses cell-autonomous induction of chaperones under chronic stress caused by misfolded proteins, allowing fine tuning of chaperone levels within the tissues of an organism [55]
doi: 10.1210/clinem/dgz024 191 WatkinsAMWoodCRLinMTAbbottBD
