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Herein, we explore the role of the gut microbiota in BB generation in humans, and the impact of preceding dietary history and oral l-carnitine supplementation on both BB generation and catabolism to TMA/TMAO in subjects

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L-carnitine is the biologically active form of carnitine, which is found in the body, in food and in most nutritional supplements

Also shown are the adverse clinical outcomes associated with elevated systemic TMAO levels in subjects, and enhanced cardiometabolic phenotypes observed with elevated TMAO levels in animal models (46, 12, 13, 1618)

Effect of lactoferrin supplementation on inflammation, immune function, and prevention of respiratory tract infections in humans: a systematic review and meta-analysis