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As an example, Zhang et al found that the rate of leakage was unchanged in patients and that higher leakage volumes were observed mainly in the range of low leakage rates, in the order of noise ratio, suggesting that BBB leakage in these cSVD patients was subtle (521)

Cambridge University Press, Cambridge, UK, pp

It worked in most, but given the weekly commitment with short term results, it was impractical for most

Step 2 FDA Review of Recommendations: The FDA considers the panel's conclusions alongside internal review

The COVID-19 ibuprofen controversy: A systematic review of NSAIDs in adult acute lower respiratory tract infections