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Negative correlation among vitamin B12 levels, obesity severity and metabolic syndrome in obese children: A case control study The Correct Way to See It On average, people with low B12 are less healthy than people with normal B12 levels

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Do not use this table as a guarantee of when specific effects will appear

For those with chronic conditions like IBD or EPI, ongoing management of the underlying disease is necessary, and periodic B12 monitoring may be recommended to ensure levels remain adequate

Animal models extend further, with 90-day rat toxicology data published in 2021 showing no organ damage at doses up to 50mg/kg daily, but extrapolating rodent data to human long-term safety requires caution we don't take lightly