intracellular glutathione pools are heterogeneously concentrated SLC33A1 exports oxidized to maintain endoplasmic reticulum redox homeostasis A mathematical model of glutathione

Effect of chlorogenic acid on disordered glucose and lipid metabolism in db/db mice and its mechanism

Formulators should focus on mechanism-driven approaches, clinically supported next-generation ingredients, and modern delivery formats, while avoiding high-dose antioxidant blends that blunt adaptive responses, he said

Next, we determined how ALS-linked mutations in FUS/TLS affected association with U1-snRNP components, using isogenic cell lines expressing a single copy of LAP-tagged wild-type and ALS-linked FUS/TLS mutations R495X, R514G, R521G and P525L

Neurodegenerative diseases: a decade of discoveries paves the way for therapeutic breakthroughs

Enhancer of zeste homolog 2 (EZH2) is a subunit of the polycomb repressive complex 2 (PCR2) and high level of EZH2 has been observed in different cancers including bladder cancer, non-small-cell lung cancer as well as colorectal cancer [78]