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Description
This changes purine and pyrimidine metabolism, and is related to DKD[195]

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D., Lu J., et al., Transplantation of Fecal Microbiota From Patients With Irritable Bowel Syndrome Alters Gut Function and Behavior in Recipient Mice, Science Translational Medicine 9, no

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The muscles become heavy, painful, and weak because they are quite literally drowning in acidic byproducts that the dysfunctional mitochondria cannot clear
