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An automatic electronic vacuum pump was used to extract part of the air (the simulated altitude decompression speed of 2 m/s) in the cabin to simulate the plateau (altitude of 6000 m)

However, the typical symptoms in a CKD patient, such as tiredness, impaired cognition, muscle weakness, myalgia, and muscle wasting, were found significantly attenuated and improved the health of patients as well as the kidney [69]

US Department of Health and Human Services, National Institutes of Health, Office of Dietary Supplements