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Synthetic mRNAs, which transiently express functional cystinosin, have demonstrated beneficial and sustained impacts on proximal tubular resorptive function, proteinuria, and kidney morphology in zebrafish after treatment [157]

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According to the US Environmental Protection Agency (EPA), Australia has a concentration of arsenic (As) above 10,000 mg per kilogram hacters, and 41% of the world's 1.4 million sites poisoned with arsenic are in the US (Smith et al

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Targeted therapies that include Bcl- 2 inhibitors have improved apoptosis, yet the development of resistance has constrained the utility of these therapies (Lampson and Davids 2017)