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A reduction or an absence of T regulatory cells significantly affects SLE evolution by autoimmune responses going unchecked [5]

This assessment is even more relevant if it is considered that the oxidized state would lead to an intramolecular disulfide bond, which usually could not lead to a single reduced Cys residue under reducing conditions, but must allow two bonds with mPEG-MAL, unless the second Cys residue is structurally or spatially hidden

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Zheng et al., 2017

using PEA incorporated into an emollient lotion