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Even unprocessed red meat at this frequency causes iron overload (inhibiting TPH1 activity) and elevates fecal pro-inflammatory Enterobacteriaceae abundance (308, 309)

It is worth noting that isolated, mildly elevated B12 in an otherwise well person taking supplements typically requires no urgent action beyond stopping non-prescribed supplementation and rechecking levels after an appropriate interval (usually 8-12 weeks)

Using it for a multi-dose vial is asking for bacterial growth in a protein-rich solution