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Research in rodents indicates that apart from the activation of MMP2, the peptide might also activate fibroblasts, which produce and maintain MMP2 and other components of the extracellular matrix, such as collagen and elastin

Friques AG, Arpini CM, Kalil IC et al (2015) Chronic administration of the probiotic kefir improves the endothelial function in spontaneously hypertensive rats

USA 102 , 93009305 (2005)