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Am J Pediatr Hematol Oncol

The second reaction requiring vitamin B12 catalyzes the conversion of homocysteine to methionine and is catalyzed by methionine synthase (also known as homocysteine methyltransferase)

Another piece of evidence suggests that the irreversible inhibition of thioredoxin reductase is the key mechanism underlying As 2 O-induced breast cancer cell apoptosis [117]

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