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Thus, it indicated the method selectivity Table 5

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Additionally, rhein alleviates desmoplastic anemia and EMT by influencing the Ras-related C3 botulinum toxin substrate 1/NOX1/-catenin signaling pathway ( Interestingly, rhein reversal of DNA hypermethylation-associated Klotho suppression ameliorates renal fibrosis (Zhang et al., 2016), and it also provides renal protection through the regulation of DNA methyltransferases expression and methylation at the Klotho promoter (Zhang et al., 2017)

J Drug Assess

Tea is a beverage that is most extensively consumed and prepared from the leaves of Camellia sinensis