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J Infect Dis 164:436437 Hector RF, Laniado-Laborin R (2005) Coccidioidomycosisa fungal disease of the Americas

There is both preclinical and clinical evidence consistent with the notion that the weakening of self-control mechanisms correlates with impaired performance in PFC circuits secondary to drug-induced adaptations in striatal networks or sometimes by direct harm to PFC (320, 356)

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L-ascorbic acid oxidizes the copper(II) ion in GHK-Cu, neutralizing both actives
