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Additionally, both cell lines exhibited a substantial reduction in cell viability and IC 50 values when treated with MNPs within the PM complexes under SMF exposure after 24 h ( Figurse 4B, D )
Kupffer cells are central in the removal of nanoparticles from the organism
The expression of inducer 61 (Cyr61), IL-23, and granulocyte-macrophage colony-stimulating factor (GM-CSF) (Ganesan and Rasool, 2019)
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Higher concentrations mean smaller injection volumes but less room for dosing error
