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while the abundance of the natural 13 C-labeled metabolite in MCF7 cells cultured with 13 C 3 -lactate for 12 h was calculated using the following formula: abundance of natural 13 C-labeled metabolite = abundance of non- 13 C-labeled metaboliteP 0

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Regulatory constraintsspanning DSHEA/FDA/EFSA limits on disease claims, substantiation standards for structurefunction statements, ingredient/novel-food authorization, raw-material identity testing, cGMP batch documentation, and post-market surveillancemay restrict labeling and clinical uptake in PD