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Such thermo-contractile and self-adjusting hydrogels provide continuous wound coverage and controlled drug release under fluctuating oxidative and mechanical conditions, as demonstrated in recent diabetic wound models

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8.2 Future research imperatives 8.2.1 Advanced risk assessment and exposure monitoring The integration of cutting-edge technologies offers transformative opportunities for EED research advancement

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It is important to note that, at the time points when we observed GPX4 level reduction under cystine starvation, there was no obvious ferroptosis induction (or any cell death) in these cell lines (most of which, such as UMRC6 and NCI-H226 cells 24 , exhibit high SLC7A11 expression and are ferroptosis resistant)