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doi: 10.1182/blood.2019003990 81 HoJLZhuBHeSDuBRothmanR

Agarwal A, Leisegang K, Majzoub A, Henkel R, Finelli R, Selvam MKP, et al

While no significant differences were found in choline, betaine, dimethylglycine, folate, total homocysteine, cystathionine, methylmalonic acid, S-adenosylhomocysteine (SAH), S-adenosylmethionine (SAM), the presence of 11 sphingomyelin species was significantly reduced in patients with prostate cancer as compared to benign hyperplasia (236)

The prevalence rates of UMI and IMI range between 6% and 27% and 30% and 58%, respectively [236,237]

It is first reduced with sodium borohydride to ethyl -bromo--hydroxybutyrate, which then reacts with trimethylamine to form a quaternary ammonium salt, ethyl bromotrimethylammonio--hydroxybutyrate