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Description
There are a handful of small human case reports, but no proper clinical trials

Most users experience no serious side effects

Lu XM, Long H (2018) Nicotinamide N -methyltransferase as a potential marker for cancer

At T24, Optimum 2.0 users showed higher serum vitamin D concentrations and fewer vitamin D deficiencies than Optimum 1.0 users, while the opposite was observed at T36 with 26% of the Optimum 2.0 users being vitamin D deficient compared to 2% of the Optimum 1.0 users

CD38 primarily functions as a NAD+-glycohydrolase (42)
