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NAD(P) H oxidase generates ROS from a pool of NADH

NM has received speaker fees from Mundipharma and Boehringer Ingehlheim on subjects unrelated to this article

The Kinase-Glo Reagent is then added to terminate the PKA reaction and detect the remaining ATP via a luciferase reaction

A new study in Nature Metabolism reveals a previously unappreciated role for selenium-based chemical species as direct electron donors to reduce ubiquinone, thus contributing to redox homeostasis by preventing lipid peroxidation

The reversible nature of the nonoxidative PPP branch and the allosteric regulation of enzymes in this pathway enable the PPP to adapt to the metabolic demands of cells, operating in different modes