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Long-term follow-up of globus pallidus chronic stimulation in advanced Parkinson's disease

doi: 10.20546/ijcmas.2017.601.004 112 MugnainiC.SannioF.BrizziA.Del PreteR.SimoneT.FerraroT.et al
Adrian S, Scherzinger A, Sanyal A, Lake JE, Falutz J, Dub MP, Stanley T, Grinspoon S, Mamputu JC, Marsolais C, Brown TT, Erlandson KM

Increased NO levels ensure stabilization and accumulation of p53, but activation of p53 suppresses NOS2 activity in a negative feedback manner [332]
However, long-term outcomes and flare rates are unknown, so steroid-free induction cannot be recommended until further evidence is available
