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95 enrolled patients with Parkinsons disease and age and gender-matched Parkinsons disease-unaffected individuals, and found earlier onset of hair graying and dysregulated sebum production, while another study revealed altered Ca and Mg levels in hair samples from patients with Parkinsons disease across disease stages 96

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Both the genetic manipulability of nematodes and their homology with mammals in the genes related to the lipid metabolism are effective advantages for investigating the regulators of body fat, lipid regulation pathways, and metabolism-related disease mechanisms