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In fact, it has been observed that aberrant NFE2L2 transcript variants missing exon 2, or exons 2 and 3, are present in lung cancers and head and neck cancers

Additionally, glutamate plasma levels are increased with the occurrence of subclinical atherosclerosis (Lehn-Stefan et al., 2021)

Recent studies have shown that upregulation of FAO occurs predominantly in conditions of nutrient deprivation, with dual inhibition of FAO (using etomoxir) and glucose metabolism (using 2-deoxy-D-glucose [2-DG]) yielding significant benefits in animal models of glioma [123]

Danons disease (DD) is an X-linked single-gene disease in which vision loss can begin at a young age