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Huntington disease: advances in the understanding of its mechanisms

Goings, J

In elderly patients with depression, a recent cross-sectional study revealed that reduced abundance of Akkermansia in the gut microbiota leads to increased levels of free fatty acids (FFA), contributing to cognitive decline (170) ( Figure 1A )

Although we do have a natural supply of NAD+ in our bodies, our levels actually decline at a cellular, tissue/organ, and organismal levels during the course of ageing and throughout time

Drug-induced liver injury (DILI) is a cause of acute and chronic liver disease caused specifically by medications and the most common reason for a drug to be withdrawn from the market after approval