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Prevention of oxidant-induced cell death by lysosomotropic iron chelators

The results showed that cells with suppressed GPX3 expression were more susceptible to cell death induced by ascorbate, indicating that GPX3 expression is crucial for scavenging excessive extracellular H2O2

In this study, we show that nearly half of the human thyroid cancer specimens have increased GPX4 expression compared to control normal thyroid tissue and that the GPX4 overexpression is associated with worse overall survival

The interplay of glutathione-related processes in antioxidant defense

This makes it an invaluable asset in the long-term management of gastric health