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Description
Aneuploidy underlies brefeldin A-induced antifungal drug resistance in Cryptococcus neoformans
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doi: 10.1038/nrc2069
Besides the purely structural role of some disulfide bonds, various effects can be ascribed to redox changes, as they can participate in catalytic, regulatory, protective and signaling mechanisms by promoting conformational changes and influencing proteinprotein interactions or subcellular localization which in fine affect the biological activity of the modified proteins
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