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The change extends the proteins half-life and permits it to disrupt normal FOXO4 function

[DOI] [PubMed] [Google Scholar] 138.Yamakawa T, Tanaka S, Numaguchi K, Yamakawa Y, Motley ED, Ichihara S and Inagami T

Up to 28 days from the first puncture, provided the vial is kept refrigerated and the stopper is wiped with alcohol before each access

The study subjects were all undergoing standard treatment with metformin, sulfonylureas, or both
