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[DOI] [PubMed] [Google Scholar] 470.Breen, D

Mannitol: It has not been demonstrated to be effective in managing cerebral edema caused by hyperammonemia and therefore, it should not be given, 43 strong recommendation, low quality evidence (1C)

1 Neurohacking may have some preventive value and many individuals are drawn to neurohacking as a means of building brain wellness and staving off age-related diminishment of brain function

Importantly, misoprostol can cause pregnancy termination or complications so must not be used unintentionally by women who are pregnant or may become pregnant

We used the search strategy in Appendix S1 and searched through Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, Embase, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Psychological Information Database (PsycINFO), and the World Health Organization International Clinical Trials Registry Platform for all available studies comparing LC alone or in combination with other standard treatments to treat PCOS