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Glioma Tumor cells may acquire resistance to therapies, leading to stress-induced autophagy activation that promotes tumor growth and recurrence [3, 204]

J Alzheimers Dis 59:481501 Mandel SA, Amit T, Weinreb O, Youdim MB (2011) Understanding the broad-spectrum neuroprotective action profile of green tea polyphenols in aging and neurodegenerative diseases

Low insulin-like growth factor-1 could also indicate problems in the liver or kidneys as these organs are most responsible for producing it

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Correctly, dopaminergic neurons are exposed to additional oxidative stress produced by the dopamine metabolism, generating H 2 O 2 and dopamine autoxidation, which generates superoxide (Delcambre et al., 2016