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Beijnen, J.H.M

The authors showed that chronic (8 week) treatment of benfotiamine improved spatial memory, and reduced amyloid plaque and phosphorylated tau levels in amyloid precursor protein (APP)/presenilin-1 transgenic mice

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EGCG exerts its protective effects through multiple mechanisms, including antioxidant activity, anti-inflammatory properties, and modulation of cellular signaling pathways

it's a potent non-stimulant small molecule that selectively inhibits Nicotinamide N-methyltransferase (NNMT), an enzyme primarily found in adipose tissue and the liver