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Once translocated into systemic circulation, LPS activates toll-like receptor 4 (TLR4), triggering NF-B-mediated release of proinflammatory cytokines ( e.g ., TNF-, IL-6) and further aggravating insulin resistance and ovarian inflammation ( Sex hormone metabolism is also modulated by the gut microbiota

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Many people ask, what is the cause of stretch marks? The main reasons are rapid stretching of the skin, hormonal changes, and sometimes genetics