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10.1016/S1474-4422(08)70167-4 Lancet Neurol
In these patients, vitamin B9 deficiency is primarily attributed to poor diet, malabsorption, chronic illness, or drugs such as alcohol and barbiturates (, )
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Mice injected with high-dose VitC (4 g/kg IP daily) in combination with radio-chemotherapy (5 mg/kg carboplatin weekly, 12 Gy IR/2 fractions (fx)) significantly increased overall survival (~ 50% increase), sensitizing these hard-to-treat NSCLC and GMB tumours to current treatment regimens
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