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Interactions between genetic and environmental factors affecting mother before and during pregnancy, e.g., chemicals (arsenate, mercury, lead, polychlorinated biphenyls, toluene, and pesticides), perinatal injuries, infections during pregnancy, hypoxia, preterm delivery, and intensive antibiotic therapies during pregnancy disturbing embryogenesis, are thought to significantly impact ASD occurrence [2]

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Thomson PA, Malavasi ELV, Grnewald E, Soares DC, Borkowska M, Millar JK (2013) DISC1 genetics, biology and psychiatric illness

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