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Apart from C0, low cutoff values have not been defined for the acylcarnitine species, relying heavily on a single metabolite (C0) for the identification of patients at risk for primary carnitine deficiency

Use with caution in pregnant or breastfeeding women, as safety data in these populations are limited

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Thus, the glycolysis pathway would be downregulated and gluconeogenesis would be upregulated

Nutritional supplement interventions include homocysteine-lowering B vitamins, niacin, vitamin B12, vitamin E, vitamin D, magnesium, zinc, iron, omega-3 fatty acids, riboflavin, coenzyme Q10 (CoQ10), lipoic acid, soy phytoestrogens, ginger, turmeric, carnitine, 5-hydroxytryptophan (5-HTP), palmitoylethanolamide (PEA), and multi-ingredient formulas