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SAH is a potent competitive inhibitor of methylation reactions and prompt removal of adenosine and Hcy is required to prevent accumulation of SAH

Its found in high concentrations in animal products, especially red meat, and is essential for red blood cell formation, DNA synthesis, brain development, and nervous system function

22 ALC serves a variety of functions in the nervous system, liver, and kidney, with an important role in mitochondrial energy homeostasis and detoxification

[72] identified an association between a specific GSH peroxidase 1 gene variant and reduced cerebral GSH levels in ME/CFS patients, which may exacerbate oxidative stress

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