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The simulations suggested that quinone metabolism yielded an increase in ROS (O 2 . and H 2 O 2 ), producing a maximum of 0.42 M and 1 10 3 M respectively
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The 16.8-fold increase in t (from 2.0 min to 33.6 min) significantly prolongs systemic circulation, reducing the need for frequent dosing [42]
doi: 10.1016/j.molimm.2022.06.003 73 PeyssonnauxCCejudo-MartinPDoedensAZinkernagelASJohnsonRSNizetV
Thiaminase I can be found in fish, ferns, some bacteria, and crustaceans, while Thiaminase II is detected in a few bacteria
