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Vascular obstruction by lipid-rich plaques This 68-year-old man presents with bilateral exertional lower extremity pain relieved by rest, absent pedal pulses, and atrophic skin changes in the setting of multiple cardiovascular risk factors

Clinical observations have demonstrated that plasma betaine levels in patients with cirrhosis are associated with disease severity and decrease after liver transplantation, indicating their association with disease progression (137)

Heme as key regulator of major mammalian cellular functions: Molecular, cellular, and pharmacological aspects

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It is better to accompany it with vitamin C to promote antioxidant activity and skin conditions in case of a proper intake
