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Despite advances in medical care, pneumonia remains a primary cause of hospitalization and mortality, especially among vulnerable groups such as the very young, the elderly, and those with preexisting health issues [2]

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At the BBB, the IR serves two primary functions: (1) mediating the transport of circulating insulin into the brain, a mechanism with potential for targeted drug delivery

Corticosteroids are generally thought to weakly suppress neutrophilic inflammation, although several research groups reported them to inhibit the neutrophil respiratory burst and interfere with neutrophil recruitment (Strausbaugh and Rosen, 2001

doi: 10.1006/bbrc.1997.7206