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Copper deficiency impairs the activity of copper-dependent enzymes such as CCO and SOD1, resulting in mitochondrial dysfunction and compromised antioxidant defense (118,170)

Lipotropic injections should be viewed as supportive to a healthier lifestyle

If the underlying disease process has resolved and cobalamin body stores have been replenished, serum cobalamin concentration should be supranormal [higher than normal] at the time of reevaluation

Parenteral vitamin B12 treatment The classic treatment for vitamin B12 deficiency is by parenteral administration, as intramuscular (IM) injections in main countries, in the form of cyano- and, more rarely, hydroxyl- (also called hydroxo-) or methyl-cobalamin, especially for this later for the treatment of genetic deficiencies [10,11]

It supports detoxification