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Interestingly, it has been found that this syndrome can also be caused by a mutation in the mitochondrial ribosomal protein MRPS22 with deficiencies of OXPHOS complexes I, III, and IV in fibroblast mitochondria [392]
Remember that iron is a cofactor nutrient that the body needs to manufacture carnitine
Behavioral strategies form the foundation: fixed wake times (more important than fixed bedtimes), morning bright light exposure for 30 minutes upon waking, evening light restriction and screen hygiene, and regularized meal times and exercise
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Bmj (2011) 343:d5928
