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This impairment results in increased apoptosis, particularly in renal proximal tubular cells, exacerbating kidney dysfunction [145]

A claim with an E/M service and two separate procedures might show: Line 1, 99214-25, the E/M with modifier 25

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, Dbrowska K., Hadera M

This results in the transcriptional upregulation of pro-inflammatory cytokines (IL-1, TNF-, IL-6) [32], chemokines (CXCL8/IL-8, CCL2), antimicrobial peptides, and co-stimulatory molecules that enhance immune cell recruitment and activation [34]