inhibition of insect glutathione s-transferase gst by conifer extracts transferases: substrates, inihibitors and pro-drugs in cancer and neurodegenerative diseases Application of Sustainable Natural Resources
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10.1016/j.plefa.2008.09.013

Figure9 shows that under normal circumstances, a 10 g dose does not cause much liver damage

Inou, S

Vartak D, Gemeinhart RA: Matrix metalloproteases: underutilized targets for drug delivery

A person should speak to their doctor if they have any concerns about nutritional supplements.