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Clinically, such insights may pave the way for combination strategies, for example pairing JAK inhibitors with modulators of innate immune activation, thereby improving long-term repigmentation stability

There are also promising treatments in development for the management of bronchiectasis, including novel anti-inflammatory therapies

Consequently, the targeted regulation of iron ion homeostasis has emerged as an effective strategy for the prevention and treatment of numerous major diseases, with new clinical pharmacological agents being widely implemented [7]

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Marks JL, Hofstetter WL, Correa AM, Mehran RJ, Rice DC, Roth JA, Walsh GL, Vaporciyan AA, Erasmus JJ, Chang J, Maru D, Lee JH, Lee J, Ajani JA, Swisher SG